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刘莹
2012-04-25 17:04:38   浏览次数:0  文字大小:【】【】【

欢迎来到抗体工程实验室

研究方向

本课题组以支撑肝脏蛋白质组学研究为目的,致力于单克隆抗体的快速、通量化制备方法的建立,人类重要生理功能和重大疾病相关蛋白抗体库的建设及抗体产品的研发、应用等,并进行抗体制备、鉴定等相关技术服务。

发表论文:

1.     Gao J, Gao Y, Ju Y, Yang J, Wu Q, Zhang J, Du X, Wang Z, Song Y, Li H, Luo X, Ren F, Li J, Chen Y, Wang L, Xu H, Liu X, Wang J, Zhang Y, Cai Y, Cui Y, Qian X, He F, Li M, Sun QH. Proteomics-   based generation and characterization of monoclonal antibodies against human liver mitochondrial proteins.  Proteomics 2006; 6:427-37. 

2.     Ning Y, Wang Y, Li Y, Hong Y, Peng D, Liu Y, Wang J, Hao W, Tian X, Wu F, Dong W, Wang L, Wu Q, Liu X, Gao J, He F, Qian X, Sun QH, Li M. An alternative strategy for high throughput generation and characterization of monoclonal antibodies against human plasma proteins using fractionated native proteins as immunogens.  Proteomics 2006; 6:438-48.

3.     Chen ZC., Yang JJ., Liu R. Wang W, Liu XL., Liu Y., Gao JE., Sun QH. 2007. Preparation and identification of monoclonal antibody against Homo Sapiens Hemo globin alpha2 (HBA 2). Journal of Experimental Hematology, 15: 823-826.

4.     He X., Yang JJ., Liu Y., Liu XL., Chen Y., Gao JE., Sun QH. 2007. Identification of protein antigen for antibody DBD02 by biopanning of T7 phage display library. China Journal Cell Molecular Immunology, 23: 847-849.

5.     Chen ZC., Yang JJ., Liu R., Wang W., Liu XL., Liu Y., Gao JE., Sun QH. 2007. Generation and characterization of monoclonal antibody against GRHPR. China Journal Cell Molecular Immunology, 23: 844-846.

6.     Qu HX., Chen ZC., Yang JJ., Liu R., Wu Q., Liu L., Chi J., Liu Y., Liu XL., Gian P. VisentinGao JE., Hu HP., Sun QH. 2007. Generation and characterization of mouse monoclonal antibody against human ALDH1A1. Chinese Journal of Hepatology, 15:867-868.

7.     Zhang YC., Liu Y., Yang JJ., Liu XL., Chi J., Gao JE., Tang XB., Zhu DL., Sun QH. 2008. Preparation and characterization of antibodies against clusterin. Chinese Journal of Cellular and Molecular Immunology 24:45-48

8.      Li SZ., Liu Y., Chen M., Liu XL., Tang XB., Gao JE., Zhu DL., Sun QH. 2008. Generation and characterization of mouse monoclonal antibody against PLA2G13. Chinese Journal of Cellular and Molecular Immunology 24: 389-392.

9.     Liu Q, Guo YR, Liu Y, Liu XL, Liu J, Zhong F, Gao JE, Sun QH. Expression of procalcitonin and characterization of antibodies against PCT. 细胞与分子免疫学杂志(Chin J Cell Mol Immunol  2008;24(8):795-797.

10.  Chen M, Yang JJ, Li SZ, Liu XL, Liu Y, Zhang LJ, Gao JE, Sun QH. Preparation and preliminary application of rabbit anti-human PON2 antibodies (paraoxonase-2). 细胞与分子免疫学杂志(Chin J Cell Mol Immunol 2008;24(7):699-702.

11.  Zhe Yu, Li Liu, Xiaobo Yu, Jun Chi, Huanhuan Han, Ying Liu, Wei He, Qihong Sun, Jianen Gao, Danke Xu. High-Throughput Antibody Generation Using Multiplexed Immunization and Immunogen Array Analysis. J Biomol Screen. 2010 15(10):1260-1267.

12.  ZHANG Ying-chun, LIU Ying, YANG Jin-ju, LIU Xiao-lan, CHI Jun, LIU Jing, GAO Jian-en, TANG Xiao-bo, Zhu Da-ling, SUN Qi-hong Preparation and identification of antibodies against FHR4免疫学杂志 2010. Immunological Journal 12:1043-1047.

13.  于占红,杨金菊,刘 静,迟俊,陈苗,柳晓兰,刘莹, 高建恩,孙启鸿PON2单克隆抗体的制备与初步鉴定细胞与分子免疫学杂志(Chin J Cell Mol Immunol2009:25(12):1130-1132.

14.  YANG Bing-fen , LIU Rong, LIU Ying, YANG Jin-ju, LIU Xiao-lan, Gao Jian-en, SUN Qi-hong Prepared the monoclonal antibody associated with hepatocellular carcinoma and analyzed its epitope Chin J Cell Mol Immunol (in press) .

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